HOME | DD

DarthFar — When Microbes Talk

Published: 2009-07-13 05:57:55 +0000 UTC; Views: 2943; Favourites: 43; Downloads: 47
Redirect to original
Description Cole watched in disbelief as the slimy little blobs slowly inched their way across his table, leaving sticky trails behind them.

They were fluorescing, which meant that they were expressing the reporter gene, which in turn showed that recombination was successful. On the other hand, quorum sensing on this scale had never been observed in either of his two specimens... and Cole had the dim recollection of accidentally tipping the petri dish open as he was reaching for a bottle of alcohol. Had something else managed to get in? or had a random genetic event just happened?

Whatever it was, he found the movement of the slugs unsettling. They were distinctly ignoring the various loose ends spotting his table, moving towards a larger, pulsating mass near his test tube rack - and even the isolated slugs were no longer static, but slowly changing course. That suggested an ability to resolve multiple images simultaneously, which in turn hinted at an uncanny ability to form images. And the fact that the stalk on the central mass was bending away from the glass beaker he'd absent-mindedly set down beside it demonstrated an eerily fascinating avoidance response. And they were growing...

He was putting his observations together, and extrapolating on them to form increasingly wild speculations. If they could communicate on this level, if they were this aware of their surroundings, they might be able to anticipate change. Have circadian rhythms. Even be capable of learning. If so, ...who knows what they could do! Many microorganisms carried out certain activities only at high cell density. Bioluminescent bacteria only flashed at fish when they were in a crowd. Pseudomonas aeruginosa only secreted its damaging enzymes where the population number was high enough for its activity to be cost effective. What were these aggregating microbes saying to each other? Proposing sex? Discussing the gastronomical merits of different agar? Trading information? -- Plotting a massive takeover of the laboratory?

On the one hand, it *could* mean groundbreaking news in the microbiology world. On the other hand, it could also mean that his hard work had gone right down the toilet.

The hell with it! I don't care if they're sentient, Cole reflected sourly, so long as they're cultured.


-------------------------------------------

100 Pictures Challenge #58: Kick in the Head.

I'm sorry for the pun! I'm sorry for the pun! I'm sorry for th-- You know what? I'm going to put the blame on Isaac Asimov and his "Shah Guido G." tale. Well, all of his humourous tales. They've totally messed up my idea of "funny". That, and I just happen to like shaggy dog stories.

I just needed to do something fun, utterly silly and without artistic (or, for that matter, scientific) merit. Mind you, though, it may be corny sci-fi, but I swear I didn't make up most of the "facts"!


What's Real (And What's Not)
(for those who really want to know)

Reporter genes are "markers" used in genetic engineering to determine if the genes of interest have been successfully incorporated or expressed in a culture. Among the common reporter genes are those encoding for fluorescent/bioluminescent proteins.

Quorum sensing - or "microbe speak" - is a real phenomenon whereby microorganisms communicate with one another through the secretion of chemicals. They use it to signal to one another about food, personal space, numbers (the examples I gave are real), aggregation, gene exchange. And yes, sex too. ("Hey babe, check out my pilus. It's skinny - but it's looong!").

Why not communicate with sound? Because, to produce sound, you would need equipment that is at least as big as the wavelength of the sound you're making. And then there's the problem of the medium in which microbes usually live - and the fact that they'd be hearing not only sounds they produce but also the mighty hammering of molecules upon their tiny bodies. Makes you think the next time you swear at your radio, doesn't it?

A number of microbes have demonstrated ability to form visible structures under certain conditions, such as the slime mold Dictyostelium discoideum, which gathers when there isn't enough food to form a large fruiting body to send out spores. Their locomotion speed is closer to about 20 um/minute, though, so in reality Cole would probably have had to sit around for 10 hours, watching them aggregate...

It is possible to resolve multiple images and form images without vision or hearing. Some species of spore-propelling fungi have demonstrated ability to sense and distinguish between gaps in obstacles, and adjust their aim accordingly.

The bit about avoidance behaviour is also observable in some species of fungi, whereby solid objects placed within several millimetres of their growing zone causes their sporangiophores to bend or grow away from it. Some scientists proposed that the sporangiophores emit volatile chemicals into the air, and detect changes based on air current and reflection of these chemicals.

The presence of free-running circadian rhythm has been demonstrated in different microorganisms (yes, even certain bacteria), among them the dinoflagellate Gonyaulax polyedra, which flashes in the water at night and photosynthesizes in the daytime (both of which require precious nitrogen supply).

So far, only a few microorganisms like Vorticella and certain flatworms and nematodes have displayed associative learning behaviour. No reason why I can't play the outrageous game of "What if?" with other classes of microbes, though!

To know more about quorum sensing, please read this article:
Small Talk in the Microbial World .

This picture is filed under "Cartoons" because there is no subcategory for "Humourous drawings".


Would anyone like a free drawing? Tell me what agar is in the tubes, and what the results are. Not you, Ty.
Related content
Comments: 59

Dabull04 [2009-09-23 18:59:56 +0000 UTC]

Very nice Mr Far

👍: 0 ⏩: 1

DarthFar In reply to Dabull04 [2009-09-24 12:06:34 +0000 UTC]

Thanks, David!

👍: 0 ⏩: 1

Dabull04 In reply to DarthFar [2009-09-26 11:27:50 +0000 UTC]

Welcome

👍: 0 ⏩: 0

Frandarts [2009-07-29 14:10:42 +0000 UTC]

I love this, particularly the way you've colored and shaded everything, and that last line. XD And his expression!

Oooh, and now I actually know something about microbes thanks to you.

👍: 0 ⏩: 0

LiZn [2009-07-18 18:49:54 +0000 UTC]

The agar slant reminds me of Christensen's urea slants, but the color doesn't seem quite "magenta" enough for a positive result. Then again, the color on this monitor kind of sucks. Off of the top of my head, that's about the only metabolic test on an agar slant I am familiar with that would have a result distinct enough to be recognized right off.

👍: 0 ⏩: 0

IcyAshford [2009-07-18 01:15:58 +0000 UTC]

Yay for nerdy Microbio talk!

👍: 0 ⏩: 0

DobbyKnits [2009-07-17 22:31:32 +0000 UTC]

"Tell me what agar is in the tubes, and what the results are."

John Agar, a.k.a. Professor Clete Ferguson from "Revenge of the Creature" (1955) (which also featured a very brief cameo by Clint Eastwood.

An amusing bit of trivia, John Agar also portrayed Dr. Clete Ferguson in "The Naked Monster " (2005). (To my knowledge, Clint was not available for this production.)

The result is: "The Revenge of the Naked Creature" by Alimar Productions (production company of such well-known titles as "Hollywood Hot Tubs 2: Educating Crystal," (1990) "Dangerous Curves," (1988) and "Party Camp" (1987).

Do I win? Huh? Tell me! Tell me!

👍: 0 ⏩: 1

WraithTen In reply to DobbyKnits [2009-07-22 02:16:25 +0000 UTC]

You deserve *something* for all of that research! LOL

👍: 0 ⏩: 1

DobbyKnits In reply to WraithTen [2009-07-22 02:58:59 +0000 UTC]



I *think* what I deserve is a swift kick in the butt as impetus to stop spending so much time online instead of going to the community center!

Still and all, I hope the Dark Nephew of Doom will see fit to give me *something* nice for my efforts.

btw - Did you get my Digital Portal thingy? If so, did you recognize my contribution to the image? It's a bit of a visual joke, though not hysterically funny. Just a rather droll kind of amusing.

👍: 0 ⏩: 0

Madman42q [2009-07-16 20:33:41 +0000 UTC]

...as long as they're cultured.
I needed that.

Nice work. Cartoonish, but excellent detail. Great story, too!

👍: 0 ⏩: 0

SvenjaLiv [2009-07-16 13:15:38 +0000 UTC]

Nice! I love the look on his face. And the story, too; I know barely enough about biology to be able to get it, which turns out to be more than I thought I knew about biology... Anyway, yeah, I really like the idea. Although, dude, how does your mind work that you come up with this stuff?!

👍: 0 ⏩: 0

FracturedReality [2009-07-15 02:51:51 +0000 UTC]

The substance: Liquid Gizka.
The result: Hostile takeover.

Or maybe it's just mango juice.

Btw, I laughed my ass off at this.

👍: 0 ⏩: 1

DarthFar In reply to FracturedReality [2009-07-15 03:40:40 +0000 UTC]

No no no, gizka agar's what's in the big media bottle in the cabinet.

Glad it amused you!

👍: 0 ⏩: 1

FracturedReality In reply to DarthFar [2009-07-18 01:54:54 +0000 UTC]

-squints- Oh, I see!

👍: 0 ⏩: 0

psychoticdustbunny [2009-07-14 00:22:28 +0000 UTC]

"What were these aggregating microbes saying to each other? Proposing sex? Discussing the gastronomical merits of different agar? Trading information? -- Plotting a massive takeover of the laboratory?"

First sex so they can reproduce, followed by a plot to take over the world and then a cookbook. Then a world tour to promote it. They have seen your cooking and are not about to put up with it anymore.

I thought everyone's microbes talked to them.

👍: 0 ⏩: 1

DarthFar In reply to psychoticdustbunny [2009-07-14 09:55:13 +0000 UTC]

What do *yours* say to you?

👍: 0 ⏩: 1

psychoticdustbunny In reply to DarthFar [2009-07-14 15:44:11 +0000 UTC]

"Feed me."
"Love me."
"Brush my hair"
"Point me in the direction of your nuclear reactor"

You know. The usual.

👍: 0 ⏩: 0

WraithTen [2009-07-13 22:52:07 +0000 UTC]

"rif lip" is the only thing I got. I tried to figure out the -G on that bottle but I couldn't. About the tubes, I have no idea what is in them but I want to know. HOW CAN A LIQUID DO THAT? My only thoughts were that perhaps it was a magnetic element and there was metal nearby.

Okay, this is awesome. First of all, I love your stories. Why does Cole remind me of a combination of you and David Ducovny from the movie "Evolution"? I loved that movie, and these little microbes remind me of the ones in the movie as well. I think you and Ty should get together and write a movie.

I really like his expression and the style of the painting, sometimes almost vectorish. It was really nice seeing this up in your gallery. Great job!

👍: 0 ⏩: 1

DarthFar In reply to WraithTen [2009-07-14 02:13:48 +0000 UTC]

Thanks! LOL. I was tired of blending colours and stuff; I wanted to do another picture like the Han (laundry) one.

"rif lip"??? Where in space did you see THAT!

What's in the tubes *isn't* liquid. It may be a *little* liquefied in parts, but it's very much solid otherwise. You can't culture microbes on liquid slants!

[link] Closeups if you want 'em.

Oh, and we almost died laughing watching Evolution. Particularly the bit in the lab, when we saw the book on the table and shouted, "Hey look, it's BURROWS!" (Burrows' Textbook of Microbiology being the fat, hefty volume we spent a great deal of time burrowing through back in our college dyas).

👍: 0 ⏩: 1

WraithTen In reply to DarthFar [2009-07-22 02:15:20 +0000 UTC]

Thanks for the closeups, but I still want to know what is in the tubes!

👍: 0 ⏩: 1

DarthFar In reply to WraithTen [2009-07-22 17:53:01 +0000 UTC]

Agar. And bacteria colonies.

👍: 0 ⏩: 0

Chimaera-Stormhawk [2009-07-13 22:21:01 +0000 UTC]

What does the Sign say? All I caught was "Fragment Polymorphism"
Darned If I know anything about Microbiology.. I'll read it again when I'm more lucid and less sleep deprived

👍: 0 ⏩: 1

DarthFar In reply to Chimaera-Stormhawk [2009-07-14 01:39:06 +0000 UTC]

"Detection of Wild Strain Pigrarium decidiosa using Restriction Fragment Length Polymorphism." Y'know, it's a diagnostic tool for the Bacterial-Inserted Genetically Acquired Laziness Syndrome (BIG-ALS).

👍: 0 ⏩: 1

Chimaera-Stormhawk In reply to DarthFar [2009-07-14 12:27:05 +0000 UTC]

Ah,Ok.

👍: 0 ⏩: 0

davincipoppalag [2009-07-13 18:56:26 +0000 UTC]

Nice work!

👍: 0 ⏩: 1

DarthFar In reply to davincipoppalag [2009-07-14 09:54:27 +0000 UTC]

Thanks, David.

👍: 0 ⏩: 1

davincipoppalag In reply to DarthFar [2009-07-14 12:03:49 +0000 UTC]

Welcome sir

👍: 0 ⏩: 0

robokop [2009-07-13 17:46:06 +0000 UTC]

Hahaha - how cute!

👍: 0 ⏩: 1

DarthFar In reply to robokop [2009-07-14 10:17:29 +0000 UTC]

Thanks!

👍: 0 ⏩: 1

robokop In reply to DarthFar [2009-07-14 22:08:22 +0000 UTC]

You are welcome!

👍: 0 ⏩: 0

Svera [2009-07-13 17:43:39 +0000 UTC]

You certainly have the most strange ideas I love the pun, too!

👍: 0 ⏩: 1

DarthFar In reply to Svera [2009-07-14 10:17:21 +0000 UTC]

I don't think "normal ideas" and "Far" get along too well. Thanks!

As Tory said, "The punning, it burns!!!"

👍: 0 ⏩: 1

Svera In reply to DarthFar [2009-07-15 16:40:03 +0000 UTC]

I guess I've heard something like this about me, too
You're welcome

👍: 0 ⏩: 0

NatalieKelsey [2009-07-13 17:18:48 +0000 UTC]

CULTURED! I love the pun...but the image it brought up was the disgruntled scientist giving the main body a little tux jacket and top hat and monocle. Or having it play a tiny violin. Or something.

I could see you writing short stories for The Intergalactic Medicine Show or something like that.

I also liked learning stuff I didn't know about microbes. Way fun!

👍: 0 ⏩: 1

DarthFar In reply to NatalieKelsey [2009-07-15 03:21:41 +0000 UTC]

I dare you. I DARE YOU! Go drag out that tablet from wherever you've been keeping it since March, and draw that!

👍: 0 ⏩: 0

Hubby-N-Dad [2009-07-13 15:47:25 +0000 UTC]

the expression is great... "oh sh-- !!"

👍: 0 ⏩: 1

DarthFar In reply to Hubby-N-Dad [2009-07-14 10:16:42 +0000 UTC]

Gee, ya think? That's what I had in mind, too.

👍: 0 ⏩: 1

Hubby-N-Dad In reply to DarthFar [2009-07-14 16:28:52 +0000 UTC]

yep, definitely not a good thing.

👍: 0 ⏩: 0

AndrewBCrisp [2009-07-13 15:03:19 +0000 UTC]

*chuckle* Short, funny, and science fiction - I could see this being an Analog Probability Zero story.

The picture is, I think, excellent. Definitely one for the favorites!

👍: 0 ⏩: 1

DarthFar In reply to AndrewBCrisp [2009-07-14 10:16:19 +0000 UTC]

Thanks very much!

👍: 0 ⏩: 0

wincenworks [2009-07-13 11:19:16 +0000 UTC]

Shouldn't his highest concern have been whether he could reliably reproduce this experiment so he doesn't end up like the cold fusion dudes?

👍: 0 ⏩: 1

DarthFar In reply to wincenworks [2009-07-13 12:52:44 +0000 UTC]

I would gather it's why he's pissed off. This was so not part of the experiment.

👍: 0 ⏩: 1

wincenworks In reply to DarthFar [2009-07-13 12:54:19 +0000 UTC]

Fame and fortune are not dictated by whether or not it's part of the experiment, it's whether or not you can reliably reproduce the outcome then put a good marketing spin on it!

👍: 0 ⏩: 1

DarthFar In reply to wincenworks [2009-07-14 10:14:39 +0000 UTC]

Actually, in describing a new organism basically you only need to make sure there's no prior published work on such an organism, furnish phenotypic characteristics, illustrations, information on where it was collected and certain molecular data; placement of the species based on existing classifications will be made based on matching their DNA sequences with the database (NCBI would be a good place).

👍: 0 ⏩: 1

wincenworks In reply to DarthFar [2009-07-14 10:38:25 +0000 UTC]

But if you do all that do you have the right to name it Fred?

👍: 0 ⏩: 0

Pegahoul [2009-07-13 10:18:51 +0000 UTC]

cool style ^^, nice expression
...
....
.....too much information and hard words... dizzy ^^

👍: 0 ⏩: 1

DarthFar In reply to Pegahoul [2009-07-15 03:41:20 +0000 UTC]

Haha, thanks! I'm infamous for my neverending comments.

👍: 0 ⏩: 0

Maquaii [2009-07-13 08:22:57 +0000 UTC]

It's like every scientist try to create something specific, and what they end up with is not heart medicine but Viagra...
I remember getting kinda freaked once during night by the sea. I was waiting for some people and decided to run my hand in the water, and it all lighted up *l* I thought that was so awesome.

👍: 0 ⏩: 0

LatteBleu [2009-07-13 06:16:00 +0000 UTC]

Augh!

"... so long as they're cultured."

Good one, though, but AUGH!

I like Cole's musings. Reminds me of life in the lab, pun not intended.

👍: 0 ⏩: 1

DarthFar In reply to LatteBleu [2009-07-13 12:40:01 +0000 UTC]

You're equally guilty of shaggy dog stories. There's that one I remember dating back to your school days, the one that was a play on "Where there's a will there's a way."

Good times, good times.

👍: 0 ⏩: 1


| Next =>