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GoronGuy123
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[37934596]
[2015-12-21 20:03:17 +0000 UTC]
"selling rocks for $900,000"
(United States)
# Statistics
Favourites: 525; Deviations: 13; Watchers: 18
Watching: 4; Pageviews: 5259; Comments Made: 407; Friends: 4
# Interests
Favorite visual artist: butts# About me
Expecting an active user? TOO BAD WALUIGI TIME# Comments
Comments: 177
Bro plz respond. And if you do, I'll donate 2 o-o-o-o-o-o-oreos to charity(my charity, to me)
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gross………
u know there's creepy ppl who think feet are hot right
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Melanoma: Causes, Symptoms and Treatments
Written by Markus MacGill Reviewed by Dr Helen Webberley
Last updated: Wed 21 October 2015
Melanoma is not the most common type of skin cancer, but it is the most serious. There are many risk factors for melanoma, including one major risk factor that is largely avoidable - overexposure to the sun.
Melanoma is a form of skin cancer that arises when the pigment-producing cells (melanocytes) mutate and become cancerous. Most pigment cells are found in the skin, although melanoma can also occur in the eyes (ocular melanoma ) and other parts of the body, such as the intestines (this is rare). It is very rare in people with dark skin.1,2
Melanoma is just one type of skin cancer, and is much less common than basal cell and squamous cell skin cancers. However, melanoma is an especially dangerous type of skin cancer because it is more likely to spread. 1,2
This article focuses on melanoma because it accounts for the majority of deaths from skin cancer each year. Much of the information regarding the prevention and treatment of melanoma also applies to the more common, but less deadly, skin cancers and pre-cancerous lesions.2
Squamous cell carcinoma and basal cell carcinoma are two such types of non-melanoma skin cancer. Basal cell is the most common form and usually grows very slowly, rarely spreading beyond the skin. Squamous cell carcinoma also rarely metastasises. Both types are known as keratinocyte skin cancers due to their involvement of keratin-producing skin cells and their appearance under the microscope. Like melanoma, squamous cell and basal cell carcinomas are linked to sun exposure.2
Contents of this article:
Fast facts on melanoma
Here are some key points about melanoma. More detail and supporting information is in the body of this article.
- Melanoma is the rarest, but the most dangerous, form of three common types of skin cancer.
- Melanoma accounts for just 2% of skin cancer cases but almost 10,000 of the >13,000 skin cancer deaths each year (American Cancer Society).
- Numerous risk factors have been identified for melanoma, and the incidence appears to be increasing for people under the age of 40, especially in women.
- Repeated overexposure to the sun is the major avoidable risk factor for melanoma - not getting sunburnt is the best prevention against skin cancer.
- Diagnosis of skin cancer is made initially by the appearance of the skin, and confirmed by biopsy sample.
- Self-monitoring of moles and other markings on the skin helps with early detection of skin cancer.
- Treatment usually aims to completely remove skin cancer tumors, and is curative if done at the cancer's earliest stage.
Melanomas can develop on any part of the skin. Certain areas are more prone than others, however. In men, the trunk (chest and back) is most likely to be affected by melanoma. In women, the legs are the most common site of melanoma. Other common sites are the neck and face.2
Skin cancer is the most common type of cancer in the US, according to the National Cancer Institute.1
According to the American Cancer Society, about 73,870 new melanomas will be diagnosed in 2015 (about 42,670 in men and 31,200 in women), and about 9,940 people are expected to die of melanoma (about 6,640 men and 3,300 women). Almost a further 50,000 cases are diagnosed with an early form of the disease.1
Recent developments in melanoma
Grapefruit, orange juice linked to increased risk of melanoma
Grapefruit and orange juices are breakfast staples for many of us. But consuming these in large amounts may be putting us at higher risk of melanoma - the deadliest form of skin cancer - according to a new study published in the Journal of Clinical Oncology.
Scientists identify another frequently mutated gene in melanoma
A new study has defined a subgroup of mutations that are present in a significant number of melanomas and identifies a new major player. In describing their findings in the journal Nature Genetics, researchers hope they will lead to more targeted therapies for this most aggressive skin cancer.
People with fewer moles may face risk of more aggressive melanoma
While people with more than 50 moles may be at higher risk of developing melanoma, people who have fewer moles may be at greater risk of developing more aggressive melanoma.
Deadly melanoma discovery supports immunotherapy treatment for cancer
Immunotherapy has received a boost as a treatment approach for cancer, in light of research carried out by a group of international scientists led by a team at the University of California-San Francisco.
Antioxidants: helpful or harmful for melanoma?
When we think of the word "antioxidant ," we often associate it with health and vitality. A new study conducted in mice, however, suggests that antioxidants can actually double the rate of melanoma metastasis.
Number of moles on right arm could predict risk of deadly skin cancer
The number of moles on one's right arm could be used to predict the risk of melanoma - the deadliest form of skin cancer - according to a new study by researchers from King's College London in the UK.
Causes of melanoma
As with all cancers, research is ongoing into the causes of melanoma. People with certain types of skin are more prone to developing melanoma, with the following factors associated with an increased incidence of skin cancer:2,3
Change of appearance in skin moles should raise suspicion of melanoma.
- High freckle density or tendency to develop freckles after sun
- High number of moles
- Five or more atypical moles
- Presence of actinic lentigines (small gray-brown spots also known as liver spots, sun spots, or age spots)
- Giant congenital melanocytic nevus (brown skin marks present at birth - birth marks)
- Pale skin that does not tan easily and burns; light-coloured eyes
- Red or light-coloured hair
- High sun exposure, particularly if it produces blistering sunburn , and especially if sun exposure is intermittent rather than regular
- Age - risk increases with age
- Family or personal history of melanoma
- Being female
- Having an organ transplant.
Only one of the above risk factors stands out as avoidable - high sun exposure and sunburn. A report by the World Health Organization estimated that the number of early deaths worldwide caused by excessive exposure to the sun's UV (ultraviolet) radiation was 60,000 in the year 2000; many of these people died from melanoma.4
Avoiding overexposure to the sun, and taking steps to prevent sunburn, are hugely important in lowering the risk of skin cancer. This includes avoiding the use of tanning beds as these are also a source of damaging UV rays.2
Symptoms of melanomaAs with other forms of cancer, the early stages of melanoma may not produce any symptoms. This is why active surveillance is heavily promoted by cancer charities and public health organisations, so as to spot early signs of the disease. Changes in the appearance of the skin are key indicators of melanoma and are also used in the diagnostic process ).
The Melanoma Research Foundation has produced a web page that compares pictures of melanoma with those of normal moles. This American non-profit organization also lists the following symptoms and signs that should prompt suspicion of skin cancer and necessitate a visit to the doctor:5
- Skin change - a new spot or mole, or a change in color, shape or size of a current spot or mole
- Skin sore that fails to heal
- Spot or sore that becomes painful, itchy, tender or bleeds
- Spot or lump that looks shiny, waxy, smooth or pale
- A firm red lump that bleeds or appears ulcerated or crusty
- A flat, red spot that is rough, dry or scaly.
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when u see ur brother's online but he's supposed to be inactive on dA
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Well I mean it's not like my Youtube page is any good either. Just please don't ask questions.
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It's okay sis, I'm just being an idiot for no reason.
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i can be an idiot for no reason too
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Is that so? Then I dare you to uninstall Neko Atsume from my iphone, I wait it belongs to me, ohhh get rekt jfedfbvnovnwefhjbcknusvkhbdsjwebfdflnd dfvrvnmfv,mnf vhjvsdfe kbv
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nooooooooooooooooooooo cries
nya nya i dont want to
i will stay right heere
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Where did you even find that?!
Also, Spoon pets is better for brain cells.
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spoon pets……..
is where u attack helpless kawaii animals(scientists are still in dispute whether they are classified as "animals") with spoons LIKE THIS
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lawl, that gets me everytime
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www.script-o-rama.com/movie_sc…
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WHYYYYYYYYYYYYY what have i done……. to deserve this………….
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- 2 cups all-purpose flour
- 1/2 teaspoon baking soda
- 1/2 teaspoon salt
- 3/4 cup unsalted butter, melted
- 1 cup packed brown sugar
- 1/2 cup white sugar
- 1 tablespoon vanilla extract
- 1 egg
Eggs Large White
$3.49 - expires in 4 days
Eggs Extra Large White
$3.49 - expires in 4 days
- 1 egg yolk
- 2 cups semisweet chocolate chips
- Add all ingredients to list
Prep
10 mCook
15 mReady In
40 m
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?????????
I'M CONFUSED BUT I'M TRYING NOT TO LAUGH
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Awesome is defined by Merriam Webster as, “inspiring awe.” Now, you can interpret that many ways, both positively and negatively. What I think may be awesome might not be for you, or for someone else. This tutorial will define the definition of awesome, to mean inspiring awe, by being great.
By becoming awesome in your life, you will open the door to the abundance of possibilities that come with putting out awesome vibes into the world. By learning how to be awesome and putting it to use in your own life, good things will start coming and happening to you on a regular basis.
Awesomeness is a way of lifeIt’s about how you behave and interact in the world. It’s about being your greatest self and putting yourself and what you have to offer out into the world. Being awesome is waking up each morning with the intention of moving forward on your journey, progressing as a person, and wanting to do whatever you can to make a positive difference in your life and the lives of others.
Here are some examples of being awesome;
- Being optimistic and having a positive outlook
- Reaching for, finding, and living your passions and dreams
- Facing your fears and overcoming them with confidence
- Leading by examples of honesty, integrity, and thoughtfulness
- Helping others and giving back to your community, however you can
- Treating others as they deserve to be treated: with kindness and respect, unless they are not deserving (aka..not being awesome)
- Continue growing, learning, evolving, and participating in the world, helping to make a difference
- Having the courage to stand up for yourself and others
- Being able to raise your voice when no one’s listening
- Being of high character and having moral values
- Bringing out your inner creativity and showing it to the world
- etc…
To make it fair, here are some examples of how to be not-so-awesome;
- Being narcissistic and selfish, thinking only of yourself and your own needs
- Treating others badly because of your own situation
- Feeling sorry for yourself, taking your aggressions out on others, and being a Debbie downer
- Being greedy, corrupt, dishonest, unfaithful, asinine, or any other type of monster
- Being pessimistic and negative
Hopefully, you now understand a little more about how to be awesome at life. Just cleaning up some of the not-so-awesome aspects and characteristics will help you on your way to becoming more awesome in your life.
Benefits of being AwesomeThe benefits of being awesome are only limited to the amount of awesomeness you continue to attain. Like I said earlier, it’s a process, a journey. Being awesome can’t happen overnight, but if you start to practice it on a regular basis, you will begin to change as a person. More than likely, you will begin to become the person you truly want to be.
Here are some clear advantages that come from acting in a more awesome-like fashion;
- The energy of awesomeness you put out into the world causes a ripple effect and does make an impact
- You will begin to feel better and will want to be happier, healthier, and truly free
- You will be inspiring and help people in their lives, making a difference
- The journey of life will begin to feel just like that — a journey of the pursuit of greatness
I’m sure you have a good understanding of how to be awesome in your own life by now, but what about getting started? After all, getting started and taking action is one of the most difficult and underused methods of moving forward in one’s life. The good news for you is, now that you know the hardest part is just starting, you know what you’re up against.
Step 1: Listen to your inner voices
In particular, listen to your conscience and inner consciousness. This is fairly easy if you take away the mystery aspect some may have. Find a quiet place where you can be alone, just you and your thoughts. Allow yourself to clear your mind of the clutter of your everyday life and just relax. Start to ponder on your life, how things are going, and if you are truly living up to your full potential.
Step 2: Feel the Need
If, after you have thought about what your life would look like if you were being more awesome, you do not feel an inner need to change, then don’t. You have to feel it. You have to want to participate on this journey. Not everyone wants to be awesome. That’s not to say they aren’t good people, it just means they are content with their current life situation, and that’s fine.
Step 3: Start
If you feel the need to change your life and your current circumstances, all you have to do is start. Start following some of the earlier examples of ways to be awesome. Once you start doing the things in life that are awesome, you will see the effect it has on your thoughts, interactions with others, and feelings towards your life.
Ready, Set, Go!!! Be awesome and help others become awesome too.
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WHAAAAAAATTTT????????????????? WHY ARE YOU DOING THIS AHAHAHA
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To be honest, I don't know why I'm talking about your art.
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www.youtube.com/watch?v=KcAY6-…
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I'M WEIRDED OUT BUT ALSO LAUGHING MUCH
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When you don't know what to do to celebarte 14 mil: www.youtube.com/watch?v=wxSzmM…
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Funny right? Here's some more Markiplier funnyness: www.youtube.com/watch?v=nnkyIn…
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ITS MIDNIGHT GO THE HECK TO BED
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Hi ant! I didn't know you had a deviantart page
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Middy told me to come and wish you a happy birthday.
Well.... HAVE A ROTTEN DAY!
Nah, just kidding. Happy birthday, dude. 
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Oh my gaahd ITS FACES OF EVIL!!! NOOOOOOOOO!!!
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POOR MICKEY…………………………………. i dont blame him i'd jump in that flowerpot too
spiders are NASTY….
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