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Velica — Transgenics anonymous.

Published: 2008-09-05 21:18:35 +0000 UTC; Views: 12039; Favourites: 30; Downloads: 1327
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Description Mice are still the best model for mammal genetics and physiology. Small, docile and cheap these little fellas are one of the main reasons why science (specially medical science) keeps advancing so quickly.

Nowadays many labs can generate mice lacking certain genes of interest by simple manipulation of mouse embryonic stem cells. There is a huge array of "mutated" mice strains about.

I thought it would be funny if they got together and discussed their griefs.

(p53 is a very important gene, involved in the development of cancer)
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Comments: 20

MrSpanyard [2014-06-02 10:28:41 +0000 UTC]

Point mutation on p53, aka, genome guardian, doesn't have to lead to cancer right away. It can only be a silent mutartion, or a revertant one. Or maybe the mouse just dies before the mutation can actually cause any vissible effect.
Maybe the joke was "what if" maybe?

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Ph0Xy [2012-06-03 03:41:28 +0000 UTC]

Don't you mean, anonyMOUSE? I'll leave now, sorry. ):

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Velica In reply to Ph0Xy [2012-06-03 17:58:55 +0000 UTC]

hahaha

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EmmetEarwax [2010-10-21 23:08:10 +0000 UTC]

Isn't P53 the self-destruct trigger in a cell, supposed to activate if a cell has gone mutant ,detected by a white-blood immune cell and receives the "commence P53 self-destruct" command from it ?

P53 initiated self-destruct is involved in embryonic development to destroy tissues and even organs that have served their purpose (such as separating the fingers from each other, and even forming the hole that becomes the mouth, not to mention the first pair of kidneys and much of the 2nd pair, leaving us with the third pair.)

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Velica In reply to EmmetEarwax [2010-10-21 23:57:31 +0000 UTC]

Thank you Mr Wikipedia.

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Spikeghost [2010-05-20 02:31:34 +0000 UTC]

aww poor lil things

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picklenation [2010-02-17 00:41:15 +0000 UTC]

HAHAHAHAHA. THIS IS SO CLEVER!
I love it!

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Mentalrabie [2008-09-11 22:21:56 +0000 UTC]

heheh
i hope, you'll make more bio-geeky cartoons, they're funny *and* informative...
btw: is the freaks of science-series closed?

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Velica In reply to Mentalrabie [2008-09-12 08:22:24 +0000 UTC]

thanks.

Well, technically no series is ever closed but I tend to drift away from them. I've been feeling quite uninspired recently...

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Mentalrabie In reply to Velica [2008-09-12 17:48:37 +0000 UTC]

that's too bad. i *loved* your freaks of science!

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Rendan86 [2008-09-07 12:02:28 +0000 UTC]

hahahaha, this is so original. really good idea for the joke

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Velica In reply to Rendan86 [2008-09-08 09:50:57 +0000 UTC]

hahah, you are a bio-geek too!!

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Rendan86 In reply to Velica [2008-09-08 11:46:16 +0000 UTC]

yes yes! hehe, i'm a biotechnology student, so it's not extrange.
have you seen my gallery, i have some bio-geek works too, not as funny as yours, but they are bio-geek inded

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Velica In reply to Rendan86 [2008-09-08 11:51:43 +0000 UTC]

I'll definitively take a look. I'm at work now (doing some bio-geeky stuff).

Adios!

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Rendan86 In reply to Velica [2008-09-08 12:34:50 +0000 UTC]

i thought you were illustrator. what are you working on?

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Velica In reply to Rendan86 [2008-09-08 13:14:19 +0000 UTC]

I'm a researcher working with leukaemia. Well, in my case, developing mouse models for the study of leukaemia.

Drawing is just an escape!

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Rendan86 In reply to Velica [2008-09-08 19:49:25 +0000 UTC]

sounds interesting. Drawing is an scape for me too. Are you working on Portugal?

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Velica In reply to Rendan86 [2008-09-09 08:13:46 +0000 UTC]

No, I've decided to emigrate for my PhD. Working in Birmingham, UK.

Are you in Uni or are you working too?

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Rendan86 In reply to Velica [2008-09-09 18:34:49 +0000 UTC]

this is my last year of Uni, so i'm pretty scared about my future right now...

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Velica In reply to Rendan86 [2008-09-10 11:44:30 +0000 UTC]

Dont be! There is loads of work and funding. You just need to move around and dont be affraid of working abroad!!

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